Intimal Injury: Response to Various Types of Injury
نویسندگان
چکیده
منابع مشابه
Neo-intimal hyperplasia, diabetes and endovascular injury
Diabetes is a significant major risk factor for peripheral arterial disease (PAD) and critical limb ischaemia (CLI), the latter which is also the most common cause of amputation in these patients. Revascularisation of the lower extremities of such patients is imperative for limb salvage and has become First-line therapy. However, the incidence of restenosis following endovascular stenting is ve...
متن کاملNox response to injury.
Szöcs and colleagues, 1 in this issue of Arteriosclerosis, Thrombosis and Vascular Biology, have added to our understanding of the role of NAD(P)H oxidase and reactive oxygen species in vascular injury. The study was undertaken by using the rat carotid artery balloon injury model, a well-characterized model of neointimal formation. In this model, vascular balloon injury leads to medial smooth m...
متن کاملThermal preconditioning before rat arterial balloon injury: limitation of injury and sustained reduction of intimal thickening.
Heat shock proteins (HSPs) are a family of highly conserved proteins, essential to cell survival, that are induced during times of physiological stress. These proteins, when induced, can provide tolerance to subsequent injury. Several studies have documented that HSPs play an important role in the response of vascular cells to injury or stress. Whether the vasculature itself can be effectively ...
متن کاملEpileptic response to peripheral injury.
From a study of the literature it is apparent that in certain cases of reflex epilepsy there is an association between the epileptic response and peripheral injury. About one hundred years ago there was a woman who suffered from generalized epileptic convulsions. Her left arm had been amputated at about the middle of the humerus, and she later complained of localized convulsions in the stump. H...
متن کاملA biochemical and mechanical model of injury-induced intimal thickening.
In this paper, we investigate an axisymmetric model of intimal thickening using hyperelasticity theory. Our model describes the growth of the arterial intima due to cell proliferation which, in turn, is driven by the release of a cytokine such as platelet-derived growth factor (PDGF). With the growth rate tied to both local stress and the local concentration of PDGF, we derive a quadruple free ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1993
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.21.6-7_467